Ghent University Academic Bibliography

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Project: Optimization of the signal/noise ratio of electronic gate detectors currently in use in HORIBA ABX instruments

project duration
16-OCT-06 – 15-APR-07
abstract
The signal-to-noise ratio and detection sensitivity of hematologic cell couters/sizers functioning on a basis of electronic gating are markedly improved by the use of a high-impedance DC-current source for signal generation and resistance-to-voltage conversion. In addition to that, a preamlifier of high input resistance and adapted bandwith is required. Determination of the cell size histogram is based on pulse-height measurements. The accuracy of this operation is largely governed by the stability of the baseline, which actually serves as a reference. Avoidance of baseline drift demands the use of a dedicated baseline restorer, adpated to the needs.