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Project: Identification of the viral protein that mediates PRRSV attachment to the sialoadhesin receptor on primary macrophages, and determination of the minimal epitope on this protein needed for receptor interaction

project duration
16-DEC-05 – 15-DEC-06
abstract
The porcine reproductive and respiratory syndrome virus infects macrofagen via the sialoadhesin receptor. With this research, we want to investigate how the virus misuses this receptor to gain entry in the macrophage.