Project: Identification and characterisation of genes controlling longevity and ageing in an animal model.
- project duration
- 01-FEB-00 – 31-JAN-03
- We shal determine genes and physiological mechanisms that cause ageing in Caenorhabditis elegans with a view to targeting similar processes in humans. This will be achieved by an extensive, interdisciplinary analysis of a series of genetic variants that exhibit substantial life span increases. This analysis will reveal regulatory mechanisms that control ageing rate and downstream mechanisms that constitute the molecular and physiological causes of ageing.