Ghent University Academic Bibliography


Project: Development of new drugs for the treatment of malaria

project duration
01-DEC-05 – 30-NOV-10
FR900098 represents an improved derivative of fosmidomycin which inhibits the isoprenoid biosynthesis in malaria parasites. For increased efficacy FR900098 should be combined with artesunate. A 3 day treatment with this recombination is anticipated to be highly effective against P. falciparum malaria with minimal side effects. Our cluster within this integrated project aims at bringing such combination in phase II clinical trials.