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Project: Assessment of safety and colonization potential of well characterized probiotic strains in South African women with healthy and disturbed vaginal microflora by molecular methods

01/11/10 – 31/10/13

Alterations in the vaginal microbiome contribute to risk of preterm birth and increased transmission of sexually transmitted agents and HIV-mother-to-child-transmission. Exogenous supplementation of vaginal bacteria to maintain and restore a healthy vaginal microflora could lead to important intervention strategies. In this project different molecular methods will be applied to study how probiotic bacteria can influence the vaginal ecology.