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Project: Endocrine and paracrine control mechanisms of the gonadal ecdysteroid response in insects

project duration
01-JAN-04 – 31-DEC-07
abstract
The research groups will combine theire efforts and complementary expertises to investigate endocrine and paracrine regulation mechanisms of the ecdysteroid response in insect gonads by means of a "Functional Genomics" approach, based on the availability of genome sequence information, of in vitro (cell, tisseus) and in vivo bioassays and of molecular tools, such as ligands and receptor genes. The biological activity of a number of recently discovered factors will be studied and functional cross-talk between signaling pathways, including these induced by the classical insect hormones, will be explored in more detail.