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Project: Interaction of Escherichia coli fimbriae with carbohydrate receptors of porcine enterocytes and the fimbriae-specific mucosal immune response

project duration
01-JAN-07 – 31-DEC-10
abstract
Piglets are very susceptible to infection with pathogenic EScherichia coli strains that adhere with their fimbriae to small intestinal enterocytes, colonise the intestine and cause diarrhoea by toxin secretion. The aim of this project is to identify fimbrial receptors and to analyse the interaction of these pathogens with the mucosal immune system of the host.