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Project: Identification by mass spectrometry of LTBetaR dependent differentiation factors important in the development of natural killer T lymphocytes.

project duration
01-JAN-02 – 31-DEC-02
abstract
The aim of this project is the identification of new differentiation factors for NKT cells in a mice model. Based on the observation that LTBetaR mediated signalling is essential to the development and/or differentiation of NKT lymphocytes, we will investigate what specific growth factors are expressed and/or secreted by mouse embryonic fibroblasts upon stimulation with a anti-LTBeteR monoclonal antibody.