Project: Identification and functional characterization of novel cadherin-binding proteins via purification of tagged cadherins in transgenic Xenopus embryos
- project duration
- 01-JAN-09 – 31-DEC-09
- The central aim of this project is the pruification of proteins associated with E- and N-cadherin. This will be done in the context of a whole organism. For this we make use of transgenic lines of Xenopus tropicalis that express modified versions of E- and N-cadherin. THese are linked to a tag that can be used for purification. Interacting proteins will be identified usin mass spec analysis.