Advanced search

Project: Disease-modifying characteristics of LXR-dependent signaling pathways in infectious and non-infectious inflammatory lung diseases

2009-01-01 – 2014-12-31

Abstract

This study aims to unravel the molecular basis by which LXR-dependent pathways contribute to pulmonary inflammation triggered by infectious and non-infectious agents. The disease-modifying potential of LXR-dependent pathways will be investigate using LXR knockout mice and synthetic LXR agonists. Success will aid in the identification of elevant key mediators and novel inflammatory disease-related pathways, essential in triggering lung diseases