Project: Alpha-catenin mutations and acquisition of the invasive phenotype in human colon cancer cells.
- project duration
- 01-JAN-98 – 31-DEC-03
- Human colon cancer cells from the HCT-8 family regularly show mutations of the alpha-catenin gene, leading to invasiveness. It is the aim of our project to find the cause of these mutations. Methods used are cell fusion and chromosome transfer.