Project: Structure function analysis of the interaction of actin binding proteins with cellular or physiological ligands.
- project duration
- 01-JAN-97 – 31-DEC-02
- We will study protein-protein and protein-ligand interactions of actin binding proteins.We aim to understand the complex regulation of these proteins with respect to cytoskeletal dydnamics, signal transduction, cell adhesion, blood coagulation etc. We will make mutants of several actin binding proteins and investigate their biochemical behaviour. Structural studies will be initiated to understand the structure function relationship.