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Project: Interaction of NO with other neurotransmitters and role of NO in physiopathological processes in the gastro-intestinal tract.

project duration
01-JAN-96 – 31-DEC-01
abstract
Nitric oxide (NO) is an important neurotransmitter in the gastrointestinal tract, inhibiting the smooth muscle cells.The interaction with the established neurotransmitters vasoactive intestinal polypeptide, noradrenaline and acetylcholine is investigated. The role of NO in the gastrointestinal relaxation during vormiting and in the gastrointestinal problems (nausea, vormiting, prolonged intestinal transit), occurring during pregnancy, is also studied.