Project: A profound study of the anti-inflammatory condition of the mouse strain SPRET/Ei, with emphasis on the glucocorticoidreceptor and the X chromosome
- project duration
- 01-JAN-10 – 31-DEC-13
- The LPS-resistance of SPRET/Ei is genetically linked to chromosomes 2 and X, and dependent on higher glucocortiod receptor expression levels. We want to search for the basis of this higher expression, and the relation with the loci on chromosomes 2 and X. We also want to study the X-locus in more detail, to possibly identify a protecting gene.