Advanced search

Project: Quantitative deep sequencing to monitor in vivo influenza A virus quasi-species evolution in the immune host

01/10/12 – 30/09/14

Abstract
The comparison of the quasi-species evolution influenza A viruses in naive and immune hosts by the use of deep sequencing whereby the obtained escape mutations will be characterised in terms of fitness, competitive advantages and stability. Thiss will give a detailed insight in the complex dynamic nature of the influenza A virus quasi-species diversity under different immune selection pressures.