Project: Study for the role of type I and III interferons in endotoxemia and sepsis

project duration: 01-OCT-07 – 30-SEP-11
abstract: I will investigate if type I and III interferons are involved in sepsis and endotoxemia. I will investigate if type I and III IFNs play a role in gram negative and positive infection. Therefore, I will use the IFNAR1-/- and IL28Ra-/- mouse, a neutralising IFN-B or IFNAR1 antibody and expressionstudies.