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Project: Impact of Nef on dendritic to T cell transmission of HIV-1

project duration
01-OCT-11 – 30-SEP-13
abstract
The role of Nef in HIV transmission from dendritic cells to T cells will be researched. Both plain cell cultures as vaginal tissue explants will be used to study viral synapse formation and cytoskeleton dynamics in infection with wild-type or nef-mutated reporter viruses.