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Project: Influence of prebiotics on pre-emptic colonisation and resulting protection against bacterial infections of the intestine in an optimized in vitro model

project duration
01-OCT-07 – 30-SEP-11
abstract
Before intestinal pathogens cause infections, they need to attach and pnetrate the mucus layer, so they can adhere to the epithelium. A little studied effect of prebiotics is their potential to reduce the adhesion of pathogens. For this research several in vitro methods will be developed such as the extension of the SHIME with a module to simulate the intestinal surface.