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Project: Analysis of crosstalk between dietary restriction, mitochondrial function, and Ins/IGF and TOR signaling pathways that regulate life span

01-OCT-08 – 30-SEP-12

The purpose of this study is to examine the interplay between a number of mecbanisms that control life span including dietary restriction, mitochondrial function and Ins/IFG and TOR signaling. This will be achieved by disrupting each of these pathways by mutation or RNAi and measuring the effects on oxidative stress and life span.