Ghent University Academic Bibliography


Project: Application of halogenated _-lactams for the stereoselective synthesis of novel mono-, bi- and tricyclic nitrogen compounds

project duration
01-OCT-09 – 30-SEP-11
This research project aims at the preparation and stereoselective transformation of (chiral) _-lactams bearing halogenated side chains and/or _-lactams bearing aa chloro atom into biologically relevant mono-, bi- and tricyclic nitrogen compounds such as new tricyclic _-lactams and bis-aziridines. Furthermore, the development of novel entries into piperidin-3-ones and azetidin-3-ones from 4-(2-bromo-1,1-dimethoxy)-_-lactams will be studied.