Project: Structure-function analysis of the human paracaspase MALT1 in antigen receptor induced signal transduction to NF-kB dependent gene expression
- project duration
- 01-OCT-08 – 30-SEP-11
- The paracaspase MALT1 plays an important role in activation of NF-kB through T- and B-cell receptors. The aims of this project are: 1) To identifty new substrates for MALT1 and to characterize their role. 2) To identify the molecular mechanisms that regulate MALT1 proteolytic activity.