Project: Epitope mapping using VHH antibodies (nanobodies) as a tool to understand the moceluar basis of gelsolin activity in cancer cell invasion
- project duration
- 01-OCT-08 – 31-MAR-10
- Lama single domain antibodies raised against gelsolin will be used to neutralize the activity of this protein, primarily in cancer cells. By investigating where in gelsolin these nanobodies bind we can better understand how this protein contributes to malignant cell behavior.