Ghent University Academic Bibliography


Project: Improvement of porcine reproductive and respiratory syndrome virus (PRRSV) vaccines for sows

project duration
01-MAY-02 – 30-APR-04
PRRSV has a restricted tropism for macrophages in vivo. Our laboratory has recently identified the receptors allowing the entry of PRRSV into porcine alveolar macrophages. In this project, we will identify the viral proteins that bind to these receptors, immunize pigs with recombinant forms of these proteins, and check the efficacy of these subunit vaccines after challenge of pregnant sows