Project: Localization and biological function of the amino-acid sequences determining the interactions between Actin and the Actin-binding proteins.
- project duration
- 01-JAN-00 – 31-DEC-99
- A systematic amino-acid sequence analysis will be carried out on actin-capping proteins. Sequence homology corresponds with functional homology. The obtained results will be confirmed by peptide synthesis, chemical cross-linking experiments and by identification of posttranslational modifications of actin. This research will contribute to our knowledge on the regulation of the microfilament-system.