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Project: Localization and biological function of the amino-acid sequences determining the interactions between Actin and the Actin-binding proteins.

project duration
01-JAN-00 – 31-DEC-99
abstract
A systematic amino-acid sequence analysis will be carried out on actin-capping proteins. Sequence homology corresponds with functional homology. The obtained results will be confirmed by peptide synthesis, chemical cross-linking experiments and by identification of posttranslational modifications of actin. This research will contribute to our knowledge on the regulation of the microfilament-system.