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Project: Autocrine and paracrine factors in tumor invasion and metastasis.

01-JAN-00 – 31-DEC-99

It is our hypothesis that tumor progression in terms of expression of the invasive and metastatic phenotype occurs in three steps : no expression, conditional and constitutive expression. It is the aim of our project to analyse the autocrine and paracrine signals, their receptors and the related transducing systems.