Project: Studying PHYsiology with NeXt generation Molecular imaging: SPHYNX
2018-05-01 – 2022-04-30
- Abstract
The Sphynx project will build a Total body time-of-flight PET (TB-TOF-PET) scanner, with significantly improved technical capabilities, to be deployed as a research tool to study physiology in plants, large animals and humans. Where current clinical PET devices have 3 to 5 rings of detectors (plus a moveable bed) the Sphynx concept is to concatenate and integrate 20 or more detector rings, to obtain a long detector cylinder. The device will be large enough to house large subjects for single-shot imaging, will have a 20-fold improved sensitivity, fourfold longer axial field of view, and twofold better spatial resolution (compared to state of the art clinical PET). It is supported by a large scientific Flemish community of engineers, pharmacists, bioengineers, clinical and veterinary specialists
The specific domains studied within human, animal, and plant physiology are neurology, oncology, endocrinology, gastroenterology, paediatrics, and plant ecophysiology.Results from Sphynx may lead to new clinical therapies (drugs, cellular therapy, radiotherapy, surgical procedures, transplantation strategies, …)and solutions for agriculture, forestry and ecosystem management.
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- Journal Article
- A1
- open access
Quantitative analysis of patient motion in walk-through PET scanner and standard axial field of view pet scanner using infrared-based tracking
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- Journal Article
- A1
- open access
A simulation study of the system characteristics for a long axial FOV PET design based on monolithic BGO flat panels compared with a pixelated LSO cylindrical design
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- Journal Article
- A1
- open access
Monte Carlo simulation of the system performance of a long axial field-of-view PET based on monolithic LYSO detectors
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- Journal Article
- A1
- open access
Walk-through flat panel total-body PET : a patient-centered design for high throughput imaging at lower cost using DOI-capable high-resolution monolithic detectors
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The potential of a medium-cost long axial FOV PET system for nuclear medicine departments