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Project: Unraveling the mechanism of TNF-induced glucocorticoid resistance, its role in inflammatory diseases and a possible therapeutical intervention

project duration
01-OCT-05 – 30-SEP-07
abstract
Tumor Necrosis Factor (TNF) is a cytokine that posesses a strong antitumor activity, but also has a strong shock-inducing activity, but also has a strong shock-inducing activity that leads to lethality. The goal of this project is to reduce the toxicity of TNF so it can be used systemically to treat malignant tumors.