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Project: Isolation of essential genes in the diploid yeast Candida albicans by conditional complementation of partially haploid mutants.

project duration
01-OCT-98 – 30-SEP-02
abstract
In the course of this project we want to complement C.albicans with an inducible cDNA library, the transformed cells will be subjected to a strong mutagenic treatment and those that possess a mutation in both alleles of an essential gene will be collected. To simplify the mutations we will try to create partially haploid C.albicans cells.