Project: Generation of isoform specific p120ctn knock-out-mice.
- project duration
- 01-OCT-00 – 30-SEP-02
- Human p120ctn is an armadilloprotein that can be expressed in 48 different isoforms. The function of these isoforms is s till unknown. In mouse more isoforms are also being rapported. We will try to reveal the function of thise isoforms by generating isoformspecific knock-out mice. We will also generate a conditional total p120ctn knock-out mouse.