Project: Research on the molecular action mechanism of caspase-14 and programmed cell death in the epidermis.
- project duration
- 01-OCT-01 – 30-SEP-05
- We investigate the mechanisms involved in programmes cell death during epidermal differentiation. Caspases are proteases that play an important role in the regulation of cell death. Caspase-14 expression and activation in keratinocytes is dependent on skin differentiation. In this project we focus on the role of caspas-14 during epidermal differentiation, eg identification of substrates, regulation of caspase-14 expression,…