Project: Evaluation of the toxicity and efficacy of absorption enhancers on Brachionus calyciflorus and Acion Ater.
- project duration
- 01-OCT-95 – 31-DEC-99
- The aim of this study is to develop an alternative in vivo model to observe the effect of absorption enhancers on ciliated epithelia. Rotifers and slugs were selected as model organisms. The effect of acute (24-H) and chronic (5-d) exposure of rotifers to permeation enhancers will be evaluated. SEM, TEM and fluorescence microscopy will be used to examine the effect of absorption enhancers on the ciliated apithelium of rotifers and slugs.