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Project: Effect of the feeding pattern and probiotics on the in vitro simulation of the development of the gut flora.

project duration
01-JAN-97 – 31-DEC-00
abstract
A first part of the project will consist out of the optimalisation of the Simulator of the Human Intestinal Ecosytem (SHINE), an in vitro model in which the human gut flora is simulated. In a second phase the influence of the feeding pattern and probiotics on the development of a stable microbial ecology will be investigated. Finally, the effect of bile salt hydrolytic lactobacilli on increaseol toxicity/mutagenicity in the colon will be investigated.