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Project: Identification and isolation of protective antigens from Ostertagia ostertagi with antibody probes from the abomasal mucosa and lymph nodes.

project duration
01-JAN-01 – 31-DEC-04
abstract
In this project, protective antigens, which were identified by screening with antibody probes of the abomasal mucosa and the lymph nodes, will be characterised and expressed as a recombinant, cDNA libraries will be screened with pools of antibody probes from immunised animals and non-immunised animals. Antigens which will react specifically with the pools from immunised animals will be cloned and e xpressed as a recombinant. At the same time, the native antigens will be purified and tested in a vaccination trial.