Project: Influence of the F4-receptors on antigen uptake in the gut-associted lymfphoid tissue and on the TH1/TH2 cytokine balance in the pig.
- project duration
- 01-JAN-99 – 31-DEC-02
- For the induction of mucosal immunity against diarrhea, caused by F4 positive ETEC, piglets have to bear a F4-receptor on their enterocytes. In this project, the role of the F4-receptor in the immune response is studied by comparing F4-receptor positive and negative piglets concerning antigen processing by M cells and enterocytes and TH1/TH2 cytokine balance in gut-asociated lymphoid tissue after immunisation with F4.