Project: Development of an oral vaccine to protect pigs against postweaning diarrhoea caused by F4+ enterotoxigenic EScherichia coli
- project duration
- 01-FEB-08 – 31-JAN-10
- In this project, an oral vaccine will be developed to protect pigs against F4+ E. coli induced postweaning diarrhoea. Therefore, the F4 protein or DNA will be encapsulated in nanoparticles to prevent gastro-intestinal degradation and specific lectins will be used to promote uptake through the epithelial barrier via enterocytes or M cells.