Project: Interactions of herpesviruses with host cells and immune cells and their consequences for viral spread and immune evasion
- project duration
- 01-OCT-08 – 30-SEP-12
- Herpesviruses cause lifelong infections of their host, and specific circumstances (e.g. stress stimuli) allow them to cause recurrent episodes of viral spread within and between hosts and recurrent symptoms, such as cold sores with herpes simplex virus. Specific interactions between herpesvirusesand host cells and immune cells allow these viruses to repeatedly avoid recognition by the immune system long enough to be able to spread and cause symptoms. The current research aims at identifying and elucidating such virus-cell interactions.