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Project: An integrated immunological, proteomic and transcriptomic approach towards the development of an Ascaris vaccine.

01-JAN-10 – 31-OCT-12

Round worms (Ascaris spp.) are universal parasites of the small intestines of humans and pigs. The scientific objectives of this proposal are (1) to provide a detailed definition of the nature of the protective mucosal response to the invading L3 larvae and (2) identify the parasite antigens driving this response.