Project: Identification and functional analysis of signaling molecules with a possible function in pluripotency and differentiation of embryonic stem cells
- project duration
- 01-OCT-11 – 30-SEP-14
- Human uterine and blastocyst fluids will be analyzed to identify extrinsic (environment) and intrinsic (cell-cell contacts) factors that drive the inner cell mass of a blastocyst towards pluripotency or towards differentiation. Additionally, a comparable approach will be used to test the in vitro environment of embryonic stem cells for putative factors involved in maintenance of pluripotency.