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Project: Identification and functional analysis of signaling molecules with a possible function in pluripotency and differentiation of embryonic stem cells

project duration
01-OCT-11 – 30-SEP-14
abstract
Human uterine and blastocyst fluids will be analyzed to identify extrinsic (environment) and intrinsic (cell-cell contacts) factors that drive the inner cell mass of a blastocyst towards pluripotency or towards differentiation. Additionally, a comparable approach will be used to test the in vitro environment of embryonic stem cells for putative factors involved in maintenance of pluripotency.