Project: Endogenic formation of thyreostats in farm animals.
- project duration
- 01-MAY-10 – 28-FEB-13
- Recently the 'natural' occurence of the synthetic thyreostat thiouracil (TU) in the urine of cattle was described. The formation pathway of TU was not yet revealed. With optimised methods (MS-MS, NMR, orbitrap) a number of feed sources and digestion processes will be studied. The in vitro research results will be validated in vivo through a metabolomics aproach.