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Project: Endogenic formation of thyreostats in farm animals.

project duration
01-MAY-10 – 28-FEB-13
abstract
Recently the 'natural' occurence of the synthetic thyreostat thiouracil (TU) in the urine of cattle was described. The formation pathway of TU was not yet revealed. With optimised methods (MS-MS, NMR, orbitrap) a number of feed sources and digestion processes will be studied. The in vitro research results will be validated in vivo through a metabolomics aproach.