Project: Expansion and osteogenic differentiation of human embryonic stem cells in bone regeneration
- project duration
- 01-JAN-08 – 31-OCT-12
- Human embryonic stem cells are expanded in vitro without the use of feeder-layers. After expansion cells are differentiated into the osteogenic lineage using specific culture conditions and selection of subpopulations. Teratoma formation and ectopic bone formation are evaluated in vivo in immunodeficient mice.