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Project: CO in the gastrointestinal tract: physiological role and therapeutic possibilities

project duration
01-OCT-05 – 30-SEP-09
abstract
The role of CO as relaxant neurotransmitter of the smooth muscle cells in the gastrointestinal tract, and its interaction with NO and VIP, are investigated. The possible anti-inflammatory infuence of CO is studied by evaluating the effects of "CO-releasing molecules" (CORMs) in models of postoperative ileus and inflammatory bowel diseases.