Project: Characterisation of protein-protein interactions in Toll-like receptor (TLR) induced signaling pathways
- project duration
- 01-OCT-06 – 30-SEP-09
- The molecular mechanisms that initiate and control an immune response against pathogens are the focus of this project. Toll-like receptors (TLRs) play an important role in the recognition of microbial components. In this project we will identify proteins that interact with specific TLR signaling molecules (e.g. IRAK4) and that are involved in the TLR-induced activation of NF-kB mediated gene expression.