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Project: Advanced biosystems modeling: a holistic approach incorporating submodel balancing, model structure sensitivity analysis and experimental identifiability

01-OCT-10 – 30-SEP-12

Advanced mathematical models are necessary to optimize the currently used suboptimal biosystems. However, when constructing these models, often a mismatch between spatial and bioprocess description occurs. This project develops novel mathematical methodological concepts (model structure sensitivity analysis, uncertainty propagation, experimental identifiability) in order to restore the balance between submodels taking into account experimental data availability.