Ghent University Academic Bibliography


Project: Identification and signal transduction analyses of direct and miRNA regulated MYCN targets in neuroblastoma

project duration
01-OCT-06 – 30-SEP-10
Neuroblastoma is the most frequent extracranial solid tumour in children. Despite the existence of multimodal treatments, the prognosis of most patients remains unfavourable. A subgroup of aggressive neuroblastoma tumours is characterised by amplification of the MYCN transcription factor. The identification of new MYCN target genes could result in improved treatment stategies.