Project: Screening entire proteomes for yeast-expressable fragments
2010-10-01 – 2012-09-30
Abstract
It is still at present largely unpredictable whether a given protein can be expressed in any production system, including the eukaryotic secretory system. Therefore, we would like to develop a proteome-wide protein fragment "expressability" screening technology in yeast, and manipulate the secretory system to analyze the effect on the "expressable proteome".