Project: Inhibition of quorum sensing in biofilm forming bacteria by plant extracts
- project duration
- 01-OCT-05 – 15-FEB-07
- In this project reporter systems (genetic constructs) will be developed to demonstrate quorum sensing (QS) in biofilm forming bacteria including Stphylococcus aureus, S. epidermidids, Streptococcus mutans, Pseudomonas aeruginosa and Burkholderia cepacia. Plant extracts will be tested on their capability ot inhibit QS and biofilm formation. Inhibition of QS may represent a new strategy for the treatment of persistent infections by the above bacteria.