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Project: The influence of cigarette smoke on the innate and adaptive intestinal immune response and on the pathogenesis of Crohn's disease.

project duration
01-OCT-09 – 30-SEP-11
abstract
Peyer's patches play an important role in the development of the normal mucosal immune response furthermore this is the region where first manifestations of Crohn's desease (CD) occur. Smoking has a detrimental role in CD pathogenesis we want to investigate the influence of cigarette smoke on mucosal immunity and receal how this can lead to the development of CD