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Project: Genomic and expression array analysis of neuroblastoma: identification of new targets for molecular targeted therapeutic intervention

01-FEB-03 – 31-JAN-05

Abstract
Our neuroblastoma research project is dedicated to the identification of genes that are involved in the development of this tumor. Special attention will be given to the identification of genes that are regulated by the MYCN gene, datailed genomic localisation of critical regions for 3p-and 11q-deletions and 17q gain and mutation analysis and functional analysis of candidate neuroblastoma genes.