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Project: Identification of epithelial stem cells in the process of continuous tooth replacement: study of the zebrafish

project duration
01-JAN-04 – 31-DEC-05
abstract
This study aims at collecting (1) morphological evidence for the existence of epithelial stem cells in the pharyngeal crypt epithelium of adult zebrafish, and (2) molecular evidence for the involvement of Wnt and Bmp signalisation pathways in repeated tooth renewal, and for a possible role of E-cadherin in the development of a new epithelial tooth bud.