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Project: In vivo and in vitro evaluation of ecdocrine disruptors using invertebrate model organisms

project duration
24-NOV-03 – 23-NOV-06
abstract
The steroid hormonal regulation will be investigated at whole-organism and cellular level, and in two model invertebrates: a pest insect (target) and a crustacea (non-target). Special attention goes to the usefulnees of in vitro cultured insect cells in predicting the biological activity of endocrine disruptors. The obained results contribute to a better knowledge and insights in the mode of action of and regulations by steroid hormones in invertebrates.